Dry Eye Treatment in St. Louis, MO
Research-Based Dry Eye Care You Can Trust
- Accredited TearLab Center with advanced diagnostics
- Principal Investigator on national dry eye studies
- Full treatment spectrum from drops to LipiFlow®
- Record of success backed by 450+ 5-star Google reviews
Why We're the Top Choice for Dry Eye Treatment
Optometrists and ophthalmologists across the St. Louis, MO, region refer their most complex dry eye cases to Mulqueeny Eye Centers. As an Accredited TearLab Center, our practice offers the advanced diagnostics and specialized treatment planning that other providers rely on when their patients need more than standard care. Whether your dry eye is mild or severe, our team has the tools and experience to help.

A Trusted Referral Destination
Optometrists and ophthalmologists across the St. Louis, MO, region refer their most complex dry eye cases to Mulqueeny Eye Centers. As an Accredited TearLab Center, our practice offers the advanced diagnostics and specialized treatment planning that other providers rely on when their patients need more than standard care. Whether your dry eye is mild or severe, our team has the tools and experience to help.
Research That Shapes How Dry Eye Is Treated
Sean P. Mulqueeny, OD, has served as a Principal Investigator on national clinical studies, including the PROOF Study to determine the natural progression of dry eye disease and the ONIT clinical investigation into the impact of oral nutrition on tear film health. His ongoing research directly informs the care our patients receive every day, connecting our St. Louis practice to the latest advances in dry eye science.
Two Generations of Focused Eye Care
Father and son optometrists Dr. Sean Mulqueeny and Dr. Brendan Mulqueeny bring a combined depth of experience that spans decades of clinical practice, academic teaching, and hands-on specialty care. Both serve as faculty at the University of Missouri-St. Louis College of Optometry, training the next generation of eye care providers while continuing to treat patients in St. Louis.
"Simply the best."
"I've been a patient at Dr. Sean Mulqueeny for over 14 years and see him at least twice annually for chemo induced dry eye. In order to receive the best care possible, we make a 500 mile round trip. Dr. Mulqueeny and his staff are simply the best. I personally recommend Mulqueeny Eye Centers to all my friends and acquaintances."
— William, 5-Star Review
A Regional Leader in
Dry Eye Relief
Known as a referral destination for dry eye care, our eye care specialist in St. Louis, MO, receives patients from across the region, including referrals from other optometrists and ophthalmologists seeking advanced diagnostics and treatment planning. Our team is led by Dr. Sean P. Mulqueeny, OD, a Principal Investigator on national dry eye research and a nationally recognized lecturer on ocular surface disease, and Dr. Brendan Mulqueeny, OD, who specializes in medically focused eye care and specialty contact lens fittings for patients with conditions like dry eye and keratoconus. Together, they combine clinical research, academic leadership, and a shared commitment to providing individualized care for every patient who walks through our doors.
“It’s a great feeling to know that your eyes are in great care at Mulqueeny. I am having issues with dry eye and from LASIK surgery at a different center but Dr Mulqueeny is getting me on the path to better vision and greater comfort.”
— K, 5-Star Review


Cutting-Edge Diagnostics
As an Accredited TearLab Center, our team uses LipiScan™ imaging and TearLab osmolarity testing to identify the root cause of your symptoms and guide your care. TearLab osmolarity testing measures the salt concentration in your tears, providing an objective marker for dry eye severity that helps us track your progress over time. Healthy tears depend on a balance of water, mucous, and oil. When that balance is disrupted, often by meibomian gland dysfunction, the result is persistent dryness, irritation, and discomfort. LipiScan with Dynamic Meibomian Imaging allows our doctors to assess the health of these glands in just 60 seconds, producing detailed images that shape a treatment plan built specifically for you.
“I went to see Dr Mulqueeny for a very severe dry eye condition. I was sitting every night with warm compresses to get some relief. I was ready to have surgery if it would have helped! I was given several eye drops to help my situation! After a few days the relief was amazing! I have not had to use a warm compress since I started the drops! I am able to wear mascara again which I had been unable to do with my swollen eye glands. I am extremely thankful for Dr Mulqueeny!”
— Cathy, 5-Star Review
Custom Treatment Plans
Once diagnosed, we offer a full range of treatment options, including Restasis® drops, EyePromise® EZ Tears supplements, and the TearCare® procedure, a comfortable, noninvasive solution for meibomian gland dysfunction. More advanced cases may benefit from LipiFlow thermal pulsation or biologic therapies such as amniotic membrane placement. Every plan is personalized, and every treatment is backed by clinical insight and years of dry eye leadership.

Affordable Dry Eye Care in St. Louis, MO
Dry eye is a progressive condition, and early treatment can make a meaningful difference in long-term comfort and eye health. We believe that effective care should be within reach for every patient. Mulqueeny Eye Centers accepts most major medical and vision insurance plans, and our team is happy to help you understand your coverage before treatment begins.
For patients seeking flexible payment options, we also offer CareCredit® financing so you can move forward with care on a timeline that works for your budget. Contact our St. Louis office to learn more about your coverage and discuss your options during a one-on-one consultation with our team.
Your Dry Eye Treatment Options

Restasis Prescription Eye Drops
Restasis is a prescription eye drop that helps your eyes increase their natural ability to produce tears. For patients with chronic dry eye caused by inflammation, Restasis works over time to restore healthier tear production rather than simply masking symptoms with artificial tears. Many patients begin to notice improvement within the first few months of consistent use.

EyePromise EZ Tears Supplements
Nutritional support can play an important role in managing dry eye from the inside out. EyePromise EZ Tears is a daily supplement formulated with omega fatty acids designed to support healthy tear film and reduce the chronic inflammation that contributes to dry eye symptoms. It is often recommended as part of a broader treatment plan.

TearCare Procedure
TearCare is a noninvasive, in-office procedure that applies gentle, targeted heat to the eyelids to soften and clear blocked meibomian glands. Unlike some alternatives, TearCare allows you to blink naturally during the treatment, making the experience more comfortable while effectively addressing meibomian gland dysfunction. Sessions are quick, typically completed in under 15 minutes, and many patients experience noticeable relief shortly after treatment.

LipiFlow Thermal Pulsation
For more advanced meibomian gland dysfunction, LipiFlow delivers precisely controlled heat and gentle pressure to both the inner and outer eyelid surfaces simultaneously. This helps clear gland blockages and restore the natural flow of oils essential to a stable, healthy tear film. The procedure is performed in our St. Louis office and typically takes about 12 minutes per eye.

Amniotic Membrane Therapy
In severe or complex cases of dry eye, biologic therapies such as amniotic membrane placement may be recommended. This treatment uses a thin biological tissue placed on the surface of the eye to promote healing, reduce inflammation, and support long-term comfort. It is typically reserved for patients who have not responded to other therapies and may be part of a comprehensive care plan developed by our doctors.


